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Periodontitis, Edentulism, and Accelerated Biological Aging: A Population-Based Study of Epigenetic Clocks.

Journal of periodontal research · Chen YN, Wang L, Romandini M, Michaud DS · 2026-09-23

Researchers found that severe periodontitis and tooth loss were associated with accelerated epigenetic aging (biological age advancement of 1–2 years) in adults aged 50 and over, suggesting oral disease may relate to systemic aging processes.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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