Other Research Study ✓ Peer reviewed

Dmp1 Knock-in Mice Faithfully Report and Manipulate Dmp1-Expressing Cells

Journal of Dental Research · T.H. Wang, M. Yang, Y. Liu, Y. Jin, Y.J. Hu, Y. Yang · 2026-09-24

Researchers created two new knock-in mouse models using CRISPR gene editing that accurately express markers in odontoblasts and related cells, avoiding the unwanted off-target expression seen in previous transgenic models, enabling better study of tooth and bone cell biology.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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