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Remineralization of Artificial Caries-like Lesions in Permanent Enamel by MI Paste One: Comparative Physicochemical Outcomes and In Vitro Resistance to Secondary Demineralization.

Journal of functional biomaterials · Alsayari NF, Al-Angari SS, Alhowaish LA, Alangari AS, Bedi R, Sulimany AM, Alsarheed MA · 2026-07-09

Researchers compared how well MI Paste One (containing fluoride and CPP-ACP) and other agents remineralized artificial white spot lesions in tooth enamel. MI Paste One demonstrated superior hardness retention after a secondary demineralization challenge compared to fluoride toothpaste, suggesting CPP-ACP's independent protective benefit.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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