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Prognostic Value of Selected Epithelial-Mesenchymal Transition and Immune Checkpoint Markers in Predicting Malignant Transformation of Oral Leukoplakia.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · Vijiakumar J, Kallarakkal TG, Karen-Ng LP, Siriwardena S, Tilakaratne WM · 2026-09-27

Researchers used immunohistochemistry to examine EMT and immune checkpoint markers in oral leukoplakia samples, finding that higher PD-1 expression was significantly associated with malignant transformation and shorter progression time, while EMT markers showed no statistically significant differences.

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