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Proliferative Leukoplakia.

Oral and maxillofacial surgery clinics of North America · Al-Hadlaq M, Alabdulaaly L, Woo SB · 2026-11-01

Proliferative leukoplakia is an aggressive oral lesion variant with high malignant transformation rates, commonly affecting older non-smoking women, characterized by specific genetic alterations and immune evasion markers that present diagnostic and treatment challenges requiring standardized international criteria.

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