Other Research Study ✓ Peer reviewed

Porphyromonas gingivalis-Derived Phosphoglycerol-isoC17:0-Dihydroceramide Reprograms Sphingolipid Metabolism in Human OECM-1 Oral Squamous Cell Carcinoma Cells.

FASEB bioAdvances · Yamada C, Ho A, Sanz N, Peng G, Xu R, Mao C, Yuan X, Momen-Heravi F, Edwards PC, Nichols F, Movila A · 2026-09-23

Researchers found that a specific sphingolipid produced by *Porphyromonas gingivalis* inhibits an enzyme involved in oral cancer cell survival, potentially altering cancer-promoting lipid metabolism pathways in oral squamous cell carcinoma cells.

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