Fluoride & Remin Randomised controlled trial ✓ Peer reviewed

Caries prevention with 1,000-ppm fluoride toothpaste in preschool children: a 24-month cluster-randomized controlled trial.

Journal of dentistry · Zhang J, Xie Q, Chu CH, Zhang X, Yu W, Shen Y, Lo ECM · 2026-09-30

Low-fluoride toothpaste (1,000 ppm) used daily reduced new cavities in primary teeth of preschool children over 24 months, with the greatest benefit seen in children who already had cavities at baseline.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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