Perio & Hygiene Randomised controlled trial ✓ Peer reviewed

Adjunctive Effects of a 2% Zinc Citrate Toothpaste on Plaque and Oral Microbiota in Orthodontic Patients: A Randomized Controlled Trial.

International journal of dentistry · Nguyen TTN, Le TC, Pham NQ, Pham TH, Ngo TQL · 2026-09-28

A trial compared a toothpaste containing 2% zinc citrate to standard toothpaste in orthodontic patients with plaque-induced gingivitis, measuring gingival inflammation, plaque levels, and bacterial load over 4 weeks. While the zinc citrate group showed lower inflammation and plaque at week 4, longitudinal analysis found no significant additional benefit from the zinc citrate toothpaste.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

Read the full study at the source
The Recall — the month's most significant new dental research, summarised. Free.
Browse The Recall