Perio & Hygiene Meta-analysis ✓ Peer reviewed

Association between salivary alkaline phosphatase levels and periodontal disease: a systematic review and meta-analysis.

BDJ open · Alarcón-Sánchez MA, Lomelí-Martínez SM, Ortuño-Sahagún D, Becerra-Ruiz JS, Mosaddad SA, Heboyan A · 2026-10-03

Elevated salivary alkaline phosphatase levels were associated with periodontitis compared to periodontally healthy individuals, but showed no significant difference between gingivitis and healthy controls or between gingivitis and periodontitis.

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