Context-dependent roles of microRNA-21 in oral medicine: Established oncogenic relevance in OSCC and emerging regenerative potential in MRONJ.
MicroRNA-21 appears to have opposite effects depending on context: it may help bone regeneration in medication-related jaw osteonecrosis, but promotes cancer development and treatment resistance in oral potentially malignant conditions and oral cancers. Clinical translation requires careful tissue-specific control to balance regenerative benefits against oncological risks.
A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.
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Managing the Pregnant Dental Patient
Confident, evidence-based dental care from the first trimester to the postpartum period
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