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Salivary metabolic profile in patients with oral squamous cell carcinoma and potentially malignant disorders.

Clinical oral investigations · Soiniemi L, Hyvärinen E, Mikkonen J, Jäsberg H, Kashyap B, Kullaa A · 2026-10-02

Researchers compared salivary metabolites in oral leukoplakia, lichen planus, oral squamous cell carcinoma and healthy controls, finding distinct metabolic changes across disease groups with shared alterations in pyruvate metabolism and pathways involving amino acids and glucose.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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