Paediatric & MIH Meta-analysis ✓ Peer reviewed

Orthodontic management in patients diagnosed with molar-incisor hypomineralisation (MIH): a systematic review and meta-analysis of clinical and epidemiological studies.

European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · Kloukos D, Seremidi K, Krämer N, Amend S, Gizani S · 2026-08-04

Researchers reviewed evidence on orthodontic treatment of patients with molar-incisor hypomineralisation, finding that extracting affected upper molars resulted in better spontaneous space closure than lower molar extractions, though optimal extraction timing remains unclear.

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