Perio & Hygiene Umbrella review ✓ Peer reviewed

THE ROLE OF PERIODONTITIS IN THE INITIATION AND PROGRESSION OF COGNITIVE DISORDERS: AN UMBRELLA REVIEW.

The journal of evidence-based dental practice · Giuliani C, Schmidlin PR, Fakheran O · 2026-09-01

An umbrella review of 20 systematic reviews found that periodontitis was generally associated with increased risk of Alzheimer's disease and dementia, with stronger associations for severe periodontitis; however, the underlying evidence was mostly observational and causality remains unestablished.

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