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Untargeted salivary metabolomics for early prediction of chemotherapy-induced oral toxicities in patients with oral squamous cell carcinoma.

Odontology · Krishnasamy N · 2026-10-13

Researchers used salivary metabolomics to identify chemical signatures in 60 oral cancer patients undergoing chemotherapy, finding that three metabolites (ceramide, lysophosphatidylcholine, and glutathione) could predict severe oral toxicities with high accuracy.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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