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From bioactivity to biofunctional restorative materials: reappraising terminology and evidence.

Clinical oral investigations · De Alencar Pinto Magalhães G, R Tay F · 2026-10-17

Researchers critically examined how "bioactivity" is used in restorative dentistry, finding that most direct restorative materials don't meet the strict definition of bioactivity but rather function through specific chemical or biological mechanisms, proposing "biofunctional" as a more accurate umbrella term for materials with intentional functions beyond structural repair.

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