Other Research Study ✓ Peer reviewed

Oral‐Onset Langerhans Cell Histiocytosis in a Noncompliant Adult: A Cautionary Case of Multisystem Progression

Australian Dental Journal · Ayşe Ege Selman, Burcu Karaduman, Mustafa Cenk Durmuslar, Necat Vakur Olgac, Hanife Ataoğlu · 2026-05-27

A 27-year-old man presented with oral ulcers and periodontal disease that were biopsied and confirmed as Langerhans cell histiocytosis; despite early diagnosis, his noncompliance allowed the disease to spread to multiple bone sites, ultimately requiring systemic chemotherapy.

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