Airways & Growth Study ✓ Peer reviewed

Bilateral molar extraction during growth is associated with impaired masticatory performance and reduced hippocampal BDNF and TrkB immunoreactivity in juvenile rats.

Journal of oral biology and craniofacial research · Achmad H, Syafriza D, Rahayu SR, Harlina, Aprilda AAE, Syaikah AAN, Mutmainnah N, Apriliani F, Santik YDP, Harlina, Lesmana H, Sitanaya R · 2026-11-01

Juvenile rats with bilateral molar extraction showed reduced chewing efficiency and decreased hippocampal BDNF and TrkB markers compared to intact controls, with positive correlations between these measures.

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