Perio & Hygiene Meta-analysis ✓ Peer reviewed

Association Between Oxidative Stress Biomarkers and Periodontitis in Saliva and Gingival Crevicular Fluid: A Systematic Review and Meta-Analysis.

Oral diseases · Fan ZX, Wang XY, Liu C, Yang J · 2026-10-19

A systematic review and meta-analysis of 85 studies found that periodontitis is associated with higher oxidant markers and lower antioxidant capacity in saliva and gingival fluid, though some salivary findings were not robust after statistical adjustment.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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