Perio & Hygiene Study ✓ Peer reviewed

Novel Method to Target Apical Periodontitis Worsened by Inflammatory Bowel Disease

Journal of Dental Research · M. Nakano, Y. Tanaka, M.S. Kyaw, W. Shuai, Y. Kamano, F. Toyama, T. Noguchi, F. Harada, V.V. Suresh, K. Handa, K. Mizuta, Y. Yahata, M. Saito · 2026-02-24

Researchers found that inflammatory bowel disease worsens apical periodontitis through increased inflammation and neutrophil activity in jawbone. Using a laser system to deliver an immunosuppressant directly into affected bone tissue reduced bone loss in this combined condition.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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