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O-GlcNAcylation Mediates BMP2-Induced Osteogenesis/Cementogenesis via NMIIA

Journal of Dental Research · J. Zhou, F. Shen, C. You, M. Liu, X. Xie, L. Zhao, L. Ye, J. Wang, Y. Shi · 2026-03-09

Researchers found that BMP2 enhances a sugar modification process called O-GlcNAcylation in periodontal ligament stem cells, which is essential for bone and cementum formation through a mechanism involving the cytoskeleton protein NMIIA.

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