Other Research Study ✓ Peer reviewed

Immune Landscape Reveals Biomarkers for High-Risk Oral Tongue Dysplasia

Journal of Dental Research · A. Sandell, M. Giacomini, M. Risteli, S. Kilpinen, T. Salo, A. Al-Samadi · 2026-03-16

Researchers compared immune cell patterns in oral tongue dysplasia samples from patients who later developed oral cancer versus those who did not, identifying elevated CD8+ T cells, CD68+ macrophages, and PD-1+ cells as potential biomarkers for distinguishing high-risk cases.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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