Other Research Study ✓ Peer reviewed

Distinct Involvement of X-Inactivation in Organogenesis

Journal of Dental Research · M. Kawasaki, K. Kawasaki, M. Fukushima, F. Tisna Sari, V. Utama, A. Kesuma, A. Fujita, J. Nihara, K. Ichikawa, T. Kudo, S. Ghafoor, P.T. Sharpe, Y. Fukusumi, H. Kawachi, T. Maeda, B. Franco, A. Ohazama · 2026-03-18

Researchers investigated how X-inactivation affects palate and tooth development using mutant mice, finding that abnormal cells accumulated differently in these tissues, consistently causing cleft palate but producing variable tooth defects.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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