Special Needs & Medical Meta-analysis ✓ Peer reviewed

Effect of Pilocarpine on Salivary Flow Rate in Patients With Xerostomia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Oral diseases · Parvatkar S, Wayadande S, Khorate M, Figueiredo N · 2026-10-19

A systematic review of 12 randomised controlled trials found pilocarpine improved salivary flow rate in xerostomia patients compared to placebo, with topical formulations showing more consistent benefits than systemic administration.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

Read the full study at the source
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