Aberrant Proliferation and Cell Fate Underlie Oral Defects in a Mouse Model of EvC Syndrome

Researchers used mice lacking the *Evc* gene to model Ellis-van Creveld syndrome, finding that defective primary cilia impaired cell growth in oral tissues and disrupted signaling pathways, leading to malformed teeth, frenula, and vestibular structures that mirror human disease.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.