Other Research Study ✓ Peer reviewed

Nitrate–Sialin Promotes Dentin Regeneration via Mitochondrial Rewiring

Journal of Dental Research · Z. Cao, S. Kong, O. Jiang, J. Wang, S. Wang, X. Li · 2026-05-28

Nitrate promotes regeneration of dentin-forming cells and tissue repair through a protein called Sialin that alters how mitochondria produce energy, reversing signs of cellular aging across multiple laboratory models and in mouse teeth.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

Read the full study at the source
The Recall — the month's most significant new dental research, summarised. Free.
Browse The Recall