Perio & Hygiene Study ✓ Peer reviewed

Periodontitis-Aggravated Diabetic Kidney Disease with Altered Glycolysis

Journal of Dental Research · Y. Shi, X. Zhu, J. Li, Y. Liu, C. Li, Y. Yang, X. He, H. Liu · 2026-07-03

Experimental periodontitis worsened kidney disease progression in diabetic mice through altered glucose metabolism and cellular changes, with the mTOR/HIF-1α pathway identified as a potential link between oral and kidney disease.

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