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Impact of phytosphingosine-enriched experimental toothpaste on dental enamel integrity: a combined in vitro and in situ investigation.

Clinical oral investigations · de Mattos D, Pimenta ALA, Vivanco RG, Bikker F, de Arruda CNF, de Panzeri FC · 2026-10-22

Researchers tested a phytosphingosine-enriched toothpaste against a commercial product using laboratory and volunteer studies, finding it reduced biofilm accumulation on enamel without damaging the tooth surface.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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