Extracellular vesicles at the periodontal immune-regenerative interface: coupled mechanisms and translational challenges.

Extracellular vesicles mediate communication between immune and tissue-repair cells in periodontitis, regulating inflammation and promoting healing of gingival, bone, and periodontal ligament tissues in experimental studies. Clinical translation requires standardized EV products, potency assays, and safety evaluation in disease-relevant models.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.