Airways & Growth Study ✓ Peer reviewed

Neutrophils Orchestrate Osteoclastogenesis in Orthodontic Tooth Movement

Journal of Dental Research · F. Ohori, H. Kitaura, K. Narita, A. Marahleh, J. Ma, K. Kanou, Z. Fan, A. Lin, K. Murakami, H. Kanetaka · 2026-07-09

Researchers used genetic sequencing to reveal that neutrophils direct bone resorption during orthodontic tooth movement by signalling to macrophages through tumour necrosis factor pathways, with neutrophil depletion reducing both tooth movement and osteoclast formation in mice.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

Read the full study at the source
The Recall — the month's most significant new dental research, summarised. Free.
Browse The Recall