Perio & Hygiene Meta-analysis ✓ Peer reviewed

The Effect of Chlorhexidine Mouthwash, With or Without Alcohol, on Plaque and Gingivitis: A Systematic Review and Meta-Analysis.

International journal of dental hygiene · van Swaaij BWM, Joosstens M, Van der Weijden GAF, de Vries L, Slot DE · 2026-08-06

A systematic review comparing alcohol-free and alcohol-containing chlorhexidine mouthwashes found that without brushing, alcohol-containing formulations controlled plaque somewhat better, but in brushing situations both formulations performed similarly for plaque and gingival inflammation.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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