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The median effective dose (ED(50)) of remimazolam combined with esketamine for conscious sedation in patients with dental anxiety undergoing outpatient dental surgery: a prospective, dose-finding study.

BMC anesthesiology · Che M, Kang C, Zhou C, Yang Y, Zhou Y, Yang Y, Li F, Xie D, Zhang Y, Zhang Y · 2026-07-07

Researchers determined that the median effective dose of remimazolam combined with esketamine for conscious sedation in anxious dental patients undergoing outpatient procedures was 0.069 mg/kg, with no serious breathing or circulation problems observed.

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