Airways & Growth Randomised controlled trial ✓ Peer reviewed

Effect of sequential Injectable Platelet Rich Fibrin (i-PRF) following Leukocyte-Platelet Rich Fibrin (L-PRF) on maxillary canine retraction: split-mouth randomized controlled trial.

Journal of oral biology and craniofacial research · Bhat D, Jena AK, Mangaraj M, Sharan J · 2026-09-01

Researchers compared canine retraction in orthodontic patients who received injectable platelet-rich fibrin after initial fibrin placement versus controls. The treatment group showed significantly greater tooth movement and changes in bone-remodeling markers in gingival fluid.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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