Perio & Hygiene Randomised controlled trial ✓ Peer reviewed

Comparative Efficacy of Platelet-Rich Fibrin and Enamel Matrix Derivative As Adjuncts to Non-Surgical Periodontal Therapy: A Split-Mouth Randomised Clinical Trial.

Oral health & preventive dentistry · Estrin NE, Ahmad P, Laurey S, Farshidfar N, Miron RJ · 2026-08-12

A split-mouth trial compared enamel matrix derivative and platelet-rich fibrin as additions to scaling and root planing in treating moderate-to-severe periodontitis, finding both biomaterials produced similar improvements in probing depth, clinical attachment level, and bleeding reduction over six months.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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