Comparative Efficacy of Platelet-Rich Fibrin and Enamel Matrix Derivative As Adjuncts to Non-Surgical Periodontal Therapy: A Split-Mouth Randomised Clinical Trial.
A split-mouth trial compared enamel matrix derivative and platelet-rich fibrin as additions to scaling and root planing in treating moderate-to-severe periodontitis, finding both biomaterials produced similar improvements in probing depth, clinical attachment level, and bleeding reduction over six months.
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