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From biological evidence to clinical application: a scoping review of oral fluid biomarkers in type 2 diabetic periodontitis.

Frontiers in oral health · Toby Thomas J, Joseph B, Aji NRAS, Thomas T, Sorsa T, Anil S, Waltimo T · 2026-07-28

Researchers reviewed evidence on oral fluid biomarkers in type 2 diabetic periodontitis, finding that active matrix metalloproteinase-8 and interleukin-1 beta showed consistent associations with disease markers, with multi-marker panels achieving higher diagnostic accuracy than single biomarkers, though standardization is needed before clinical use.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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