Perio & Hygiene Study ✓ Peer reviewed

IL-17 Receptor inhibition with brodalumab limits experimental periodontitis.

Journal of translational medicine · Valverde A, Naqvi RA, Tokarski M, Ceredon K, Gluck J, Elshourbagy S, Martínez G, Brambilla M, Nares S, Schwartz J, Naqvi AR · 2026-07-29

Brodalumab, an IL-17 receptor inhibitor, reduced inflammatory responses and alveolar bone loss in mice with experimentally induced periodontitis, with effects increasing at higher doses and approaching healthy levels by day 8.

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