Inflammation-Driven Epithelial Plasticity in Oral Mucosa Adjacent to Long-Term Restorative Materials: A Retrospective Histopathological and Immunohistochemical Study.

Researchers examined oral tissue samples adjacent to different long-term restorative materials and found that metallic and amalgam restorations were associated with greater tissue remodeling and inflammatory markers, while ceramic restorations showed minimal changes compared to controls.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.