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Risk Factors for a Systemic Inflammatory Response After Major Oral Cancer Surgery with Microvascular Free Flap Reconstruction: An Exploratory Retrospective Analysis.

Journal of inflammation research · Kukulenz NB, Schuerholz T, Dau M, Frerich B · 2026-08-06

Researchers examined 123 patients undergoing oral cancer surgery with free flap reconstruction to identify risk factors for systemic inflammatory response. Elevated preoperative white blood cell counts and greater intraoperative blood loss emerged as key independent predictors of this complication.

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