Perio & Hygiene Meta-analysis ✓ Peer reviewed

Effectiveness of Vitamin C in managing gingival hyperpigmentation: A systematic review and meta-analysis.

Journal of Indian Society of Periodontology · Valecha R, Rathod SR, Bajaj VA, Bawankar P · 2026-04-01

Vitamin C showed short-term improvement in reducing gingival hyperpigmentation at one month compared to conventional methods, though results varied and no significant difference emerged at three months. The review identified limited high-quality evidence and calls for more standardised research.

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