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Effects of Stromal Cell-Derived Factor 1 on Osteoblast Activity During Orthodontic Tooth Movement.

Clinical and experimental dental research · Hamada Y, Ishida Y, Huang AC, Hamahara K, Rintanalert D, Li K, Hatano-Sato K, Hosomichi J, Usumi-Fujita R, Ono T · 2026-08-01

Blocking the SDF-1/CXCR4 signalling pathway in rats reduced orthodontic tooth movement and altered bone remodeling markers in the periodontal ligament, suggesting this pathway influences osteoblast differentiation during tooth movement.

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