Paediatric & MIH Randomised controlled trial ✓ Peer reviewed

Effect of ibuprofen premedication on intraoperative pain during vital pulp therapy in MIH-affected permanent molars: a triple-blind randomized clinical trial.

BMC oral health · Faghihian R, Saatchi M, Amrollahi N, Tarrahi MJ, Ebrahimi A, Bagheri S · 2026-07-02

Children with molar-incisor hypomineralization undergoing vital pulp therapy experienced significantly less intraoperative pain when given ibuprofen premedication compared to placebo, based on two pain measurement scales.

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