Fluoride & Remin Randomised controlled trial ✓ Peer reviewed

Efficacy of Silver Diamine Fluoride on Young Children With Severe Early Childhood Caries: A Randomized Clinical Trial.

JAMA pediatrics · Fontana M, Moursi A, Gonzalez-Cabezas C, Khera D, Levy SM, Eckert GJ, Katz BP, Tenuta LMA, Campos MS, Karl E, Boynton J, Chinn C, Sheen A, Kolker J, Warren J, Thorpe E · 2026-07-27

A large randomised trial found that 38% silver diamine fluoride arrested approximately 54% of active cavity lesions in primary teeth of young children with severe early childhood caries at 6 months, substantially outperforming placebo with comparable safety profiles.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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