Direct restoration failure after head and neck radiotherapy: prevalence and independent predictors from a multicenter mixed-effects analysis.

Researchers examined direct restoration failure in 115 head and neck cancer survivors after radiotherapy, finding that 37.6% of 423 restorations failed, predominantly from secondary caries, with higher salivary flow protecting against failure while higher radiation dose, glass-ionomer material, larger restorations, age over 24 months, and endodontically treated teeth increasing failure risk.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.