Paediatric & MIH Study ✓ Peer reviewed

The role of prenatal factors in molar incisor hypomineralization: Could the 2D:4D ratio be a biomarker?

Early human development · Gülşen E, Ünal T, Kızılay FN, Gülşen İT · 2026-08-10

Children with molar incisor hypomineralization showed higher digit length ratios (a marker of prenatal hormone exposure) compared to unaffected controls, with this association particularly evident in boys, suggesting prenatal androgen exposure may influence enamel development.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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