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The Marine Triterpene Stellettin B Triggers Mitochondrial-to-Nuclear Translocation of AIF/EndoG and Reverses Epithelial-Mesenchymal Transition to Inhibit Oral Cancer Progression.

International journal of medical sciences · Chen PY, Kuo PC, Ling YL, Wang YY, Yuan SF, Sheu JH, Tsai WC · 2026-07-22

Researchers found that Stellettin B, a compound from marine sponges, inhibited oral cancer cell growth and invasion by triggering caspase-independent apoptosis and reversing epithelial-mesenchymal transition, while leaving normal oral cells largely unharmed.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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