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Repurposing Masitinib Mesylate as a Novel FOXM1 Inhibitor for the Treatment of Aggressive Solid Tumors: Preclinical Validation in Human Breast and Oral Cancer Cells and Organotypic Tumor Slice Culture.

ACS omega · Gupta R, Singh J, Shetty SD, Kumar NAN, Kudva A, Srivastava SK, Chakrabarty S · 2026-06-29

Researchers found that masitinib mesylate, an existing drug, inhibits FOXM1—a cancer-promoting protein—and reduced cancer cell growth, stemness, and migration in breast and oral cancer models, including patient-derived tumor tissues.

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