Repurposing Masitinib Mesylate as a Novel FOXM1 Inhibitor for the Treatment of Aggressive Solid Tumors: Preclinical Validation in Human Breast and Oral Cancer Cells and Organotypic Tumor Slice Culture.
Researchers found that masitinib mesylate, an existing drug, inhibits FOXM1—a cancer-promoting protein—and reduced cancer cell growth, stemness, and migration in breast and oral cancer models, including patient-derived tumor tissues.
A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.
Read the full study at the sourceRelated CPD from Vital Pulp
Managing the Pregnant Dental Patient
Confident, evidence-based dental care from the first trimester to the postpartum period
The Recall — the month's most significant new dental research, summarised. Free.
Browse The Recall