Special Needs & Medical Systematic review ✓ Peer reviewed

Clinicopathologic features and treatment outcomes of marginal gingival (ring around the collar) leukoplakia: a systematic review of emerging evidence.

General dentistry · Ferraz DLF, Santos BC, Pedroso CM, Santos-Silva AR, Lopes MA · 2026-09-01

Marginal gingival leukoplakia showed high recurrence (45.4%) and malignant transformation rates (24.2%) across 66 patients in 17 studies, with most lesions treated by scalpel excision and often displaying hyperkeratosis on histology.

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