Fluoride & Remin Review ✓ Peer reviewed

The Cariostatic Mechanisms of Fluoride-An Updated Review.

Dentistry journal · Šutej I, Bašić K, Peroš K · 2026-06-24

Fluoride prevents tooth decay primarily through topical action that stops mineral loss and promotes remineralization at the tooth surface, with effectiveness enhanced by calcium-fluoride reservoirs and microbial enzyme inhibition; standard toothpaste concentrations (1000–1500 ppm) benefit children, while higher doses suit high-risk patients.

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