Perio & Hygiene Systematic review ✓ Peer reviewed

Periodontitis and breast cancer risk: A systematic review with meta-epidemiological analysis.

Journal of periodontology · Peitoxo RK, Del Agnese CC, Comassetto MC, Oliveira LM, Miguez PA, Antoniazzi RP · 2026-07-29

A systematic review of 19 studies found women with periodontitis had a 19% higher breast cancer risk overall, but the association weakened substantially in higher-quality prospective studies with adequate adjustment for confounding factors, suggesting methodological limitations may have inflated earlier estimates.

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