Other Research Study ✓ Peer reviewed

Inflammation and Regeneration in the Dentine-Pulp Complex: Where are we now and where are we going?

Journal of endodontics · Cooper PR, Friedlander LT, Hussaini HM, Ratnayake J, Duncan HF · 2026-08-21

This narrative review synthesises recent research on how inflammation and regeneration interact within the dentin-pulp complex, exploring immune responses to caries progression and how systemic conditions like type-2 diabetes influence these processes. The authors propose that improved understanding of these mechanisms, supported by preclinical research and clinician-scientist collaboration, could enable better diagnostics and regenerative endodontic treatments.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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