Paediatric & MIH Study ✓ Peer reviewed

Study on pathogenic mechanisms of metabolic pathways and key metabolites associated with black stain with or without severe early childhood caries.

Archives of oral biology · Peng X, Wang Q, Chen L, Lin B, Zhang L, Wang G · 2026-08-18

Researchers compared dental plaque metabolites in preschoolers with black stain alone versus those with severe early childhood caries and black stain, identifying metabolic pathway differences and potential biomarkers that could help diagnose and prevent severe early childhood caries.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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